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经验公式(希尔记法):
C23H32O4
化学文摘社编号:
分子量:
372.50
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
200-275-9
MDL number:
Beilstein/REAXYS Number:
2570798
Assay:
≥98% (HPLC)
Form:
powder
产品名称
醋酸去氧皮质酮,
biological source
synthetic (organic)
sterility
non-sterile
assay
≥98% (HPLC)
form
powder
solubility
H2O: insoluble, acetone: soluble (1 in 30), alcohol: soluble (1 in 50), chloroform: freely soluble, dioxane: slightly soluble, vegetable oils: slightly soluble
shipped in
ambient
storage temp.
room temp
SMILES string
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@]([H])(CC[C@@]24[H])C(=O)COC(C)=O
InChI
1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1
InChI key
VPGRYOFKCNULNK-ACXQXYJUSA-N
Gene Information
human ... NR3C2(4306)
General description
Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one.
Application
Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats.
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存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
涉药品监管产品
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