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E2250

鞣花酸

Name: 鞣花酸
Brand: SIGMA

≥95% (HPLC), powder, from tree bark

别名:

4,4′,5,5′,6,6′-六氢二苯二甲酸2,6,2′,6′-二内酯, 鞣花酸

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关于此项目

经验公式（希尔记法）:

C₁₄H₆O₈

化学文摘社编号:

476-66-4

分子量:

302.19

UNSPSC Code:

12352205

NACRES:

NA.77

PubChem Substance ID:

24894460

EC Number:

207-508-3

Beilstein/REAXYS Number:

47549

MDL number:

MFCD00006914

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属性

biological source

tree bark

Quality Level

200

assay

≥95% (HPLC)

form

powder

shelf life

5 yr

solubility

1 M NaOH: 10 mg/mL

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

SMILES string

Oc1cc2C(=O)Oc3c(O)c(O)cc4C(=O)Oc(c1O)c2-c34

InChI

1S/C14H6O8/c15-5-1-3-7-8-4(14(20)22-11(7)9(5)17)2-6(16)10(18)12(8)21-13(3)19/h1-2,15-18H

InChI key

AFSDNFLWKVMVRB-UHFFFAOYSA-N

Gene Information

human ... CSK(1445), DYRK1A(1859), GSK3B(2932), SRC(6714)
rat ... Lyn(81515), Syk(25155)

说明

General description

鞣花酸是在多种水果和蔬菜中天然生成的酚酸类次级植物代谢物，通常存在于绿茶、石榴、草莓、树莓和核桃中。

Application

鞣花酸已用于：

基于植物乳杆菌CECT 748T研究酚酸类膳食物质的代谢机制
作为植物乳杆菌单宁酶高产的潜在底物
在荨麻酚类成分和抗氧剂活性研究中作为检测标准品
研究膳食鞣花酸和脂肪形成表观遗传调节之间的关系

Biochem/physiol Actions

研究发现，鞣花酸可抑制低密度脂蛋白的氧化，因这种抗氧化活性它对人心脏具有保护作用。此外，它也具有抗癌、抗纤维化、抗疟原虫、细胞凋亡和化学预防活性。

其是一种常见的植物多酚，是谷胱甘肽S-转移酶的抑制剂。可用于血浆中XIIa因子的测定。可在血液凝固中发生接触激活。

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存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

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E2250-5G	04061835512478
E2250-10G	04061833602539
E2250-1G	04061835516001