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关于此项目
经验公式(希尔记法):
C20H14O2S2
化学文摘社编号:
分子量:
350.45
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Quality Level
assay
≥95% (HPLC)
form
powder
color
off-white to yellow
solubility
DMSO: >20 mg/mL, H2O: insoluble
storage temp.
2-8°C
SMILES string
Oc1ccc2ccccc2c1SSc3c(O)ccc4ccccc34
InChI
1S/C20H14O2S2/c21-17-11-9-13-5-1-3-7-15(13)19(17)23-24-20-16-8-4-2-6-14(16)10-12-18(20)22/h1-12,21-22H
InChI key
RFAXLXKIAKIUDT-UHFFFAOYSA-N
Biochem/physiol Actions
IPA-3是Pak1的变构抑制剂。
IPA-3是Pak1的变构抑制剂。它与pak1(p21激活激酶)的自身抑制结构域结合,在激酶中具有高选择性。 Pak1与肿瘤发生和转移有关。
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Mathilde Gavillet et al.
American journal of hematology, 93(2), 269-276 (2017-11-11)
NET formation in mice (NETosis) is supported by reactive oxygen species (ROS) production by NADPH oxidase and histone hypercitrullination by peptidylarginine deiminase 4 (PAD4). Rac1 and Rac2, expressed in polymorphonuclear neutrophils (PMNs), regulate the cytoskeleton, cell shape, adhesion, and migration
Florian Ingo Schmidt et al.
The EMBO journal, 30(17), 3647-3661 (2011-07-28)
Vaccinia virus (VACV), the model poxvirus, produces two types of infectious particles: mature virions (MVs) and extracellular virions (EVs). EV particles possess two membranes and therefore require an unusual cellular entry mechanism. By a combination of fluorescence and electron microscopy
Ludwig Kraus et al.
Drug and alcohol review, 36(5), 626-632 (2016-06-29)
Information on high-risk drug use in Turkey, particularly at the regional level, is lacking. The present analysis aims at estimating high-risk cannabis use (HRCU) and high-risk opiate use (HROU) in the cities of Ankara, Istanbul and Izmir. Capture-recapture and multiplier
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I2285-5MG | 04061833848388 |
| I2285-25MG | 04061833219171 |

