biological source
rat
Quality Level
recombinant
expressed in E. coli
assay
≥97% (SDS-PAGE)
form
lyophilized powder
mol wt
15.5 kDa
packaging
pkg of 0.1 mg
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
color
white
UniProt accession no.
storage temp.
−20°C
Gene Information
rat ... Ifng(25712)
Application
来自大鼠的干扰素-γ已被用于研究脂氧素A4和17(R)-消退素D1对培养的大鼠星形胶质细胞中脂多糖和干扰素-γ介导的肿瘤坏死因子释放的影响。在大鼠中，它已被用于处理INS-1细胞培养物以研究可将β-细胞复制或凋亡的频率转变为复制或凋亡比率的转化因子。
Biochem/physiol Actions
Ifng（干扰素-γ）在先天性和获得性免疫反应中可起重要作用，并有助于防御细菌、双态酵母和某些病毒的感染。它在大鼠栓塞性中风的缺血性损伤中被上调。在培养的大鼠肠粘膜微血管内皮细胞中，ifng负责诱导干扰素-α和干扰素-β的表达。
Features and Benefits
生物学活性是利用抗病毒检测体系对感染了EMC病毒的L-929细胞进行测量而得到的。
Physical form
从每1 μg细胞因子含有50 μg牛血清白蛋白的磷酸盐溶液经0.2 μm过滤后冻干的。
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
低风险生物材料
此项目有
Sally Abdelmoaty et al.
PloS one, 8(9), e75543-e75543 (2013-10-03)
Lipoxins and resolvins have anti-inflammatory and pro-resolving actions and accumulating evidence indicates that these lipid mediators also attenuate pain-like behavior in a number of experimental models of inflammation and tissue injury-induced pain. The present study was undertaken to assess if
Meager, A. et al.
Lymphokines and Interferons, A Practical Approach, 129-129 (1987)
R Dijkema et al.
The EMBO journal, 4(3), 761-767 (1985-03-01)
The chromosomal immune interferon gene of the rat (IFN-gamma) was identified by screening a recombinant rat lambda phage library with a human IFN-gamma cDNA probe. In contrast to the genes of other rat IFNs, this rat IFN-gamma chromosomal gene contains
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I3275-.1MG | 04061833855942 |