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Merck
CN

M9766

4-甲基伞形酮 α- D -吡喃葡萄糖苷

α-glucosidase substrate, fluorogenic, ≥99% (TLC), powder

别名:

4-甲基伞形酮 α- D -葡萄糖苷

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关于此项目

经验公式(希尔记法):
C16H18O8
化学文摘社编号:
分子量:
338.31
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
241-794-0
MDL number:
Beilstein/REAXYS Number:
1690776
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产品名称

4-甲基伞形酮 α- D -吡喃葡萄糖苷,

Quality Level

assay

≥99% (TLC)

form

powder

solubility

pyridine: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

CC1=CC(=O)Oc2cc(O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12

InChI

1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16+/m1/s1

InChI key

YUDPTGPSBJVHCN-JZYAIQKZSA-N

Application

4-甲基伞形基ǥ-D-吡喃葡糖苷已用于测定组织匀浆中的酸性 α-葡萄糖苷酶(GAA)活性。

Biochem/physiol Actions

4-甲基伞形基ǥ-D-吡喃葡糖苷是 ǥ-葡萄糖苷酶的荧光底物。产物 4-甲基伞形花酯在荧光光谱中显示出 440nm 处的峰值。


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品

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分析证书(COA)

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Omid Motabar et al.
Analytical biochemistry, 390(1), 79-84 (2009-04-18)
Mutations in alpha-glucosidase cause accumulation of glycogen in lysosomes, resulting in Pompe disease, a lysosomal storage disorder. Small molecule chaperones that bind to enzyme proteins and correct the misfolding and mistrafficking of mutant proteins have emerged as a new therapeutic
J van Lieshout et al.
Archaea (Vancouver, B.C.), 1(4), 285-292 (2005-04-07)
Pyrococcus furiosus laminarinase (LamA, PF0076) is an endo-glycosidase that hydrolyzes beta-1,3-glucooligosaccharides, but not beta-1,4-gluco-oligosaccharides. We studied the specificity of LamA towards small saccharides by using 4-methylumbelliferyl beta-glucosides with different linkages. Besides endo-activity, wild-type LamA has some exo-activity, and catalyzes the
Nao Yamakawa et al.
Biochimie, 89(11), 1396-1408 (2007-05-29)
Sulfated sialic acid (SiaS) is a unique sialic acid (Sia) derivative in which an additional anionic group is attached to a carboxylated monosaccharide. Very little is known about the occurrence and biologic function of SiaS, due to the limitations of



全球贸易项目编号

货号GTIN
M9766-100MG04061834064558
M9766-10MG04061834064565
M9766-1G04061835557776
M9766-250MG04061835546190
M9766-25MG04061835557783