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Merck
CN

N2165

NKY80

≥98% (HPLC)

别名:

2-Amino-7-(2-furanyl)-7,8-dihydro-5(6H)-quinazolinone

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关于此项目

经验公式(希尔记法):
C12H11N3O2
化学文摘社编号:
分子量:
229.23
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
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assay

≥98% (HPLC)

form

powder

color

off-white to light brown

solubility

DMSO: ≥30 mg/mL

storage temp.

2-8°C

SMILES string

Nc1ncc2C(=O)CC(Cc2n1)c3ccco3

InChI

1S/C12H11N3O2/c13-12-14-6-8-9(15-12)4-7(5-10(8)16)11-2-1-3-17-11/h1-3,6-7H,4-5H2,(H2,13,14,15)

InChI key

SOJUSNIBPPMLCC-UHFFFAOYSA-N

Biochem/physiol Actions

NKY80 is a selective adenylyl cyclase-V inhibitor with greater than 200-fold selectivity for type V over the type II isoform.
NKY80 is a selective adenylyl cyclase-V inhibitor.

Features and Benefits

This compound is a featured product for ADME Tox and Cyclic Nucleotide research. Discover more featured ADME Tox and Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Adenylyl cyclases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

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