N3876
(−)-尼古丁
≥99% (GC), Prototype nicotinic acetylcholine receptor agonist, liquid
别名:
(−)-1-甲基-2-(3-吡啶基)四氢吡咯, (S)-3-（1-甲基-2-吡咯烷基）吡啶
选择尺寸
关于此项目
产品名称
(−)-尼古丁, ≥99% (GC), liquid
assay
≥99% (GC)
form
liquid
optical activity
[α]20/D −169°(lit.)
color
yellow
refractive index
n20/D 1.5265 (lit.)
solubility
ethanol: 50 mg/mL
density
1.010 g/mL at 20 °C (lit.)
SMILES string
CN1CCC[C@H]1c2cccnc2
InChI
1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m0/s1
InChI key
SNICXCGAKADSCV-JTQLQIEISA-N
Gene Information
human ... CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNB2(1141), CHRNB4(1143), CYP2A6(1548), KCNH1(3756)
mouse ... Chrna7(11441), Chrnb1(11443)
rat ... Chrna1(79557), Chrna2(170945), Chrna4(25590), Chrna7(25302), Chrnb2(54239), Chrnb4(25103)
General description
Application
- 在细胞外DNA荧光实验和中性粒细胞免疫染色中刺激中性粒细胞
- 通过细胞外DNA荧光检测和中性粒细胞免疫染色来研究新生儿慢性尼古丁暴露对尼古丁乙酰胆碱受体(nAChR)结合、细胞死亡和海马和小脑形态的影响
- 在体外研究中评估尼古丁或可替宁的根暴露对成纤维细胞形态和密度的影响
Biochem/physiol Actions
Preparation Note
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signalword
Danger
Hazard Classifications
Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
flash_point_f
213.8 °F - closed cup
flash_point_c
101 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
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