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O1257

油酸-水溶性

Name: 油酸-水溶性
Brand: SIGMA

powder, BioReagent, suitable for cell culture

别名:

油酸-环糊精复合物

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关于此项目

NACRES:

NA.75

PubChem Substance ID:

24897936

UNSPSC Code:

12352211

MDL number:

MFCD00064242

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属性

biological source

synthetic (organic)

Quality Level

200

product line

BioReagent

form

powder

composition

Oleic acid, ~30 mg/g (balance methyl-β-cyclodextrin)

technique(s)

cell culture | mammalian: suitable

solubility

H₂O: 50 mg/mL, clear to slightly hazy

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-

InChI key

ZQPPMHVWECSIRJ-KTKRTIGZSA-N

Gene Information

human ... SOAT1(6646), SOAT2(8435)

说明

Application

十八烯酸水溶液可用于：

制备用于细胞处理的FFA（游离脂肪酸）混合物
研究其对L6肌细胞中溶质载体家族2成员4 (SLC2A4)/GLUT4表达的影响，并用作潜在的转录调控因子
制备脂肪培养基，用于诱导原代人肝细胞的体外脂肪变性

Other Notes

甲基-β-环葡聚糖结合改善了油酸在培养基中的溶解度和运输。

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

油酸在细胞培养中的应用

不饱和脂肪酸、油酸和其他细胞培养成分如何影响无血清、无蛋白细胞培养系统（用于生物制造包括单克隆抗体在内的异源蛋白）的性能。

Oleic Acid in Cell Culture

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

Stearic Acid in Cell Culture

Supplement cell culture systems with fatty acids for biomanufacturing heterologous proteins like monoclonal antibodies.

A20 attenuates FFAs-induced lipid accumulation in nonalcoholic steatohepatitis

Ai L, et al.

International Journal of Biological Sciences, 11(12), 1436-1436 (2015)

Extra-pancreatic invasion induces lipolytic and fibrotic changes in the adipose microenvironment, with released fatty acids enhancing the invasiveness of pancreatic cancer cells.

Takashi Okumura et al.

Oncotarget, 8(11), 18280-18295 (2017-04-15)

Pancreatic cancer progression involves components of the tumor microenvironment, including stellate cells, immune cells, endothelial cells, and the extracellular matrix. Although peripancreatic fat is the main stromal component involved in extra-pancreatic invasion, its roles in local invasion and metastasis of

Oleic and linoleic fatty acids downregulate Slc2a4/GLUT4 expression via NFKB and SREBP1 in skeletal muscle cells

Poletto A C, et al.

Molecular and Cellular Endocrinology, 401(12), 65-72 (2015)

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全球贸易项目编号

货号	GTIN
O1257-10MG	04061834213161