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P4663

聚L -精氨酸 盐酸盐

mol wt 5,000-15,000

别名:

L-Arginine homopolymer hydrochloride

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关于此项目

化学文摘社编号:
26982-20-7
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24898490
NACRES:
NA.26
MDL number:
MFCD00166393
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form

powder

Quality Level

200

mol wt

5,000-15,000

color

white to off-white

application(s)

cell analysis
detection

storage temp.

−20°C

SMILES string

Cl.NC(CCCNC(N)=N)C(O)=O

InChI

1S/C18H38N12O4.ClH/c19-10(4-1-7-26-16(20)21)13(31)29-11(5-2-8-27-17(22)23)14(32)30-12(15(33)34)6-3-9-28-18(24)25;/h10-12H,1-9,19H2,(H,29,31)(H,30,32)(H,33,34)(H4,20,21,26)(H4,22,23,27)(H4,24,25,28);1H/t10-,11-,12-;/m0./s1

InChI key

PQEISBBDIRAKGR-LFELFHSZSA-N

Application


  • 聚（乙烯基胺盐酸盐）、聚（二烯丙基二甲基氯化铵）、聚-L-赖氨酸和聚-L-精氨酸与脂质双分子层相互作用的界面静电。：该研究调查了聚-L-精氨酸盐酸盐与脂质双分子层之间的相互作用，为其在药物输送系统中的潜在应用提供了深入见解（McGeachy et al., 2018）。（McGeachy et al., 2018）。

Analysis Note

分子量基于前体聚-L-鸟氨酸的粘度。
含有3%或更低的鸟氨酸残基。

Other Notes

有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。

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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLBF2407V
111M5012V
071M5001
071M5001V
055K51082

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商品

Poly(Amino Acid) Block Copolymers for Drug Delivery and other Biomedical Applications

Humankind has utilized protein materials throughout its existence, starting with the use of materials such as wool and silk for warmth and protection from the elements and continuing with the use of recombinant DNA techniques to synthesize proteins with unique and useful properties.

Analysis of transient and reversible effects of poly-L-arginine on the in vivo nasal absorption of FITC-dextran in rats.
Ohtake K, Natsume H, Ueda H, et al.
J. Controlled Release, 82, 263-275 (2002)
Poly-L-arginine enhances paracellular permeability via serine/threonine phosphorylation of ZO-1 and tyrosine dephosphorylation of occludin in rabbit nasal epithelium.
Ohtake K, Maeno T, Ueda H, et al.
Pharmaceut. Res., 20, 1838-1845 (2003)
M Miyamoto et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 52(1), 21-30 (2001-07-05)
The effects of the concentration and molecular weight of poly-L-arginine (poly-L-Arg) on the in vivo nasal absorption of fluorescein isothiocyanate-labeled dextran (MW, 4 kDa, FD-4) in rats were studied. When poly-L-Arg with a range of different molecular weights (MW, 8.9
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全球贸易项目编号

货号GTIN
P4663-100MG04061834375029
P4663-10MG04061832780122
P4663-50MG04061832780139