S143
(±)-6-Chloro-PB hydrobromide
≥98% (HPLC), D1 dopamine receptor agonist, solid
别名:
(±)-6-Chloro-7,8-dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrobromide, (±)-SKF-81297 hydrobromide
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关于此项目
经验公式（希尔记法）:
C16H16ClNO2 · HBr
化学文摘社编号:
分子量:
370.67
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
(±)-6-Chloro-PB hydrobromide, ≥98% (HPLC), solid
Quality Level
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
color
white to light tan
solubility
H2O: 1.7 mg/mL, DMSO: >10 mg/mL, ethanol: 6.3 mg/mL
SMILES string
Br[H].Oc1cc2C(CNCCc2c(Cl)c1O)c3ccccc3
InChI
1S/C16H16ClNO2.BrH/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20;/h1-5,8,13,18-20H,6-7,9H2;1H
InChI key
RMIJGBMRNYUZRG-UHFFFAOYSA-N
Gene Information
human ... DRD1(1812)
Application
(±)-6-Chloro-PB hydrobromide has been used as a dopamine D1 receptor (Drd1a) agonist to study the role of the drd1a-dopamine receptor inactivation of extracellular signal‑regulated protein kinase 1/2 (ERK1/2) in the wild-type and striatum of dopamine-depleted mice. It has also been used as a Drd1a agonist to identify the contribution of D1 (D1R)-like dopamine receptor signaling on learning and memory in Barnes maze in rats.
Biochem/physiol Actions
(+/-)-6-Chloro-PB HBr is a full D1 dopamine receptor agonist.
Disclaimer
Product is air and light sensitive
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves