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Merck
CN

SCP0037

淀粉样蛋白β1-40大鼠

≥95% (HPLC)

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关于此项目

经验公式(希尔记法):
C190H291N51O57S1
分子量:
4233.72
NACRES:
NA.32
UNSPSC Code:
12352200
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assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥75%

storage condition

protect from light

storage temp.

−20°C

Application

淀粉样β(Aβ)是指衍生自淀粉样蛋白前体蛋白的肽,其长度在36-43个氨基酸之间变化。 Aβ(s)肽,其肽片段和突变片段用于研究广泛的代谢和调节功能,包括激酶的激活、胆固醇转运的调节、作为转录因子的功能和炎症的调节因子。 Aβ(s)肽及其肽片段还用于研究氧化应激、金属结合和蛋白质交联机制,例如阿尔茨海默病和神经变性。


存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Xuehong Yu et al.
Neurobiology of learning and memory, 123, 168-178 (2015-06-14)
Single-session anodal transcranial direct current stimulation (tDCS) can improve the learning-memory function of patients with Alzheimer's disease (AD). After-effects of tDCS can be more significant if the stimulation is repeated regularly in a period. Here the behavioral and the histologic
Maryam Bagheri et al.
Neurobiology of learning and memory, 95(3), 270-276 (2010-12-15)
Alzheimer's disease (AD) is a debilitating neurodegenerative disorder characterized by increased β-amyloid (Aβ) deposition and neuronal dysfunction leading to impaired learning and recall. Ageing, heredity, and induced oxidative stress are among proposed risk factors. The increased frequency of the disease
Aynun N Begum et al.
Journal of Alzheimer's disease : JAD, 15(4), 625-640 (2008-12-20)
The rat amyloid-beta (Abeta) intracerebroventricular infusion can model aspects of Alzheimer's disease (AD) and has predicted efficacy of therapies such as ibuprofen and curcumin in transgenic mouse models. High density lipoprotein (HDL), a normal plasma carrier of Abeta, is used



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