T9028
单克隆抗-微管蛋白，酪氨酸 小鼠抗
clone TUB-1A2, ascites fluid
别名:
Anti-CDCBM6, Anti-CSCSC1, Anti-M40, Anti-OK/SW-cl.56, Anti-TUBB1, Anti-TUBB5
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关于此项目
Conjugate:
unconjugated
Clone:
TUB-1A2, monoclonal
Application:
ARR, IF, WB
Citations:
122
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
TUB-1A2, monoclonal
contains
15 mM sodium azide
species reactivity
human, plant, animal
technique(s)
indirect immunofluorescence: 1:800 using cultured chicken fibroblasts, microarray: suitable, western blot: suitable
isotype
IgG3
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TUBA4A(7277), TUBB(203068)
General description
单克隆抗络氨酸微管蛋白（小鼠 IgM 同种型）来源于杂交瘤，该杂交瘤由小鼠骨髓瘤细胞与免疫小鼠脾细胞融合产生。微管蛋白为圆柱形丝状结构，几乎存在于所有真核细胞中。微管蛋白是异二聚体，由 α-微管蛋白和 β-微管蛋白组成。 每种亚基的分子量均为55 kDa，具有相当大的同源性。
微管，是细胞内圆柱状丝状结构，主要由微管蛋白组成，存在于所有真核细胞中。单克隆抗酪氨酸抗体可通过间接免疫荧光标记，对酪氨酸 α 微管蛋白进行免疫细胞化学定位。 单克隆抗酪氨酸抗体与酪氨酸微管蛋白发生特异性反应，适用于牛脑细胞、非洲绿猴肾细胞（Vero），犬肾细胞（MDCK）、袋鼠肾细胞（Potoroo，PtK2）、小鼠垂体瘤细胞（AtT-20）、酵母细胞和非洲爪蟾细胞。
Immunogen
含有 α-微管蛋白羧基端氨基酸的肽
Application
单克隆抗酪氨酸微管蛋白用于：
- 间接免疫荧光标记
- 免疫印迹技术
- 免疫细胞化学染色
Biochem/physiol Actions
微管蛋白是微管的主要构建单元。微管蛋白的组装过程涉及微管蛋白酪氨酸化。特异性微管蛋白酪氨酸羧肽酶去除末端酪氨酸，产生末端为谷氨酸残基的 α-微管蛋白；而另一种酶通过在羧基末端添加酪氨酸修饰 α-微管蛋白，从而形成酪氨酸增加和损失的潜在循环。
该抗体在免疫印迹测定中与微管蛋白的C-末端酪氨酸反应，可用于培养细胞或组织切片中该表位的定位。
Disclaimer
除非我们的产品目录或产品随附的其他公司文件中另有说明，否则我们的产品仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、体外或体内治疗用途或任何类型的人类或动物消费或应用。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
商品
Microtubules of the eukaryotic cytoskeleton are composed of a heterodimer of α- and β-tubulin. In addition to α-and β-tubulin, several other tubulins have been identified, bringing the number of distinct tubulin classes to seven.
On some features of embryonic development and metamorphosis of Aurelia aurita (Cnidaria, Scyphozoa)
Mayorova TD, et al.
Russian journal of developmental biology, 43(5), 271-285 (2012)
Norito Kotani et al.
Biophysical journal, 93(3), 886-894 (2007-05-15)
Inner-arm dynein-f of Chlamydomonas flagella is a heterodimeric dynein. We performed conventional in vitro motility assays showing that dynein-f translocates microtubules at the comparatively low velocity of approximately 1.2 microm/s. From the dependence of velocity upon the surface density of
Hitoshi Kurio et al.
Biology of reproduction, 85(5), 924-933 (2011-07-08)
Ceacam6 (carcinoembryonic antigen-related cell adhesion molecule 6 gene) has recently been isolated by differential display followed by RT-PCR and DNA sequence analyses. Ceacam6 is a member of an immunoglobulin superfamily and encodes a protein of 266 amino acid residues possessing
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| T9028-.2ML | 04061837380327 |
| T9028-100UL | 04061838027016 |