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Merck
CN

U6628

乌发醇

≥95%

别名:

Urs-12-ene-3,28-diol

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关于此项目

经验公式(希尔记法):
C30H50O2
化学文摘社编号:
分子量:
442.72
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352103
EC Number:
208-888-3
MDL number:
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assay

≥95%

mp

223-225 °C (lit.)

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

SMILES string

C[C@@H]1CC[C@]2(CO)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C

InChI

1S/C30H50O2/c1-19-10-15-30(18-31)17-16-28(6)21(25(30)20(19)2)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h8,19-20,22-25,31-32H,9-18H2,1-7H3/t19-,20+,22+,23-,24+,25+,27+,28-,29-,30-/m1/s1

InChI key

XUARCIYIVXVTAE-ZAPOICBTSA-N

Gene Information

mouse ... Nos2(18126)

General description

Uvaolis是一种五环三萜化合物,通常从植物叶子中提取,例如罗布麻 (Apocynum venetum L.)、橄榄叶 (Olea europaea L.) 和牛至 (Origanum vulgare L.)。

Application

熊果醇已被用作视黄酸受体相关孤儿受体γ t (RORγt) 抑制剂,以研究强心苷还原酶2 (Cgr2) 对其代谢的作用。

Biochem/physiol Actions

熊果醇具有抗氧化、抗癌、抗炎和伤口愈合等药理特性。它还具有血管扩张、保肝和抗菌作用。熊果醇对一氧化氮 (NO) 释放具有抑制作用。


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Emad M Hassan et al.
Planta medica, 74(14), 1749-1750 (2008-11-01)
Phytochemical investigation of the methanolic extract of Plumeria acutifolia (Apocynaceae) leaves has led to the isolation and identification by spectroscopic means of a new monoterpene alkaloid, (R)-4'-((S)-1-hydroxyethyl)-5,6-dihydro-5' H-spiro[cyclopenta[C]pyridine-7,2'-furan)-5'-one, for which the name plumerianine was adopted, the iridoid 15-demethylplumeride, and three
Lei Liu et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 32(17), 1762-1765 (2007-11-13)
To investigate the chemical constituents of Pyrola calliatha. The chemical constituents were isolated by various column chromatographic methods. The structures were identified by spectral data. Ten compounds were isolated and identified as chimaphilin (1), uvaol(2), ursolic acid (3), 2beta,3beta,23-trihydroxy-12-ene-28-ursolic acid
B S Min et al.
Planta medica, 65(4), 374-375 (1999-06-12)
The methanol extracts of the leaves of Crataegus pinnatifida showed potent inhibitory activities against HIV-1 protease at a concentration of 100 micrograms/ml. The subsequent fractionation and isolation of the extract gave two active compounds. Their structures were identified as uvaol



全球贸易项目编号

货号GTIN
U6628-25MG04061837409929