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1140430

USP

硫酸氯吡格雷

Name: 硫酸氯吡格雷
Brand: USP

United States Pharmacopeia (USP) Reference Standard

别名:

(S)-甲基(2-氯苯基)(6,7-二氢-4H-噻吩并[3,2-c]吡啶-5-基)醋酸盐硫酸氢盐

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关于此项目

经验公式（希尔记法）:

C₁₆H₁₆ClNO₂S · H₂SO₄

化学文摘社编号:

120202-66-6

分子量:

419.90

UNSPSC Code:

41116107

NACRES:

NA.24

PubChem Substance ID:

329749435

MDL number:

MFCD00876395

Beilstein/REAXYS Number:

9967887

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属性

grade

pharmaceutical primary standard

API family

clopidogrel

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

OS(O)(=O)=O.COC(=O)[C@@H](N1CCc2sccc2C1)c3ccccc3Cl

InChI

1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1

InChI key

FDEODCTUSIWGLK-RSAXXLAASA-N

Gene Information

human ... P2RY12(64805)

说明

General description

本品按现行药典规定交付。所有为支持本产品而提供的信息，包括SDS和任何产品信息小册子，均由药典颁发机构制定和发布。

如需进一步的信息和支持，请访问现行药典网站。

Application

硫酸氢氯吡格雷USP参考标准品的预期用途是美国药典规定的指定质量测试和检测。也用于下列USP专论：

硫酸氢氯吡格雷
氯吡格雷片
氯吡格雷复合口服混悬液(Clopidogrel Compounded Oral Suspension)

Analysis Note

这些产品仅供测试和分析使用。它们不适用于人类或动物的给药，不可用于诊断、治疗或治愈任何疾病。

Disclaimer

可能适用相应的销售限制。

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pictograms

GHS05,GHS09

signalword

Danger

hcodes

H314,H411

pcodes

P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338

Hazard Classifications

Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Clopidogrel Tablets

USP43-NF38: United States Pharmacopeia and National Formulary

United States Pharmacopeia, 33(1), 1111-1111 (2020)

Counterintuitive compaction behavior of clopidogrel bisulfate polymorphs.

Kailas S Khomane et al.

Journal of pharmaceutical sciences, 101(7), 2408-2416 (2012-04-11)

Being a density violator, clopidogrel bisulfate (CLP) polymorphic system (forms I and II) allows us to study individually the impact of molecular packing (true density) and thermodynamic properties such as heat of fusion on the compaction behavior. These two polymorphs

Point-of-care measurements of platelet inhibition after clopidogrel loading in patients with acute coronary syndrome: comparison of generic and branded clopidogrel bisulfate.

Kyoung-Woo Seo et al.

Clinical therapeutics, 36(11), 1588-1594 (2014-09-15)

Platelet-function suppression with antiplatelet therapy is effective in preventing and treating cardiovascular disease. Clopidogrel is a thienopyridine derivative that blocks platelet activation by adenosine diphosphate receptor binding. This study demonstrates the effects of generic clopidogrel bisulfate in comparison to branded

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全球贸易项目编号

货号	GTIN
1140430-125MG	04061838701664