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Merck
CN

V900372

潮霉素B 来源于吸水链霉菌

Vetec, reagent grade

别名:

Hygrovetine

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关于此项目

经验公式(希尔记法):
C20H37N3O13
化学文摘社编号:
分子量:
527.52
UNSPSC Code:
51102829
PubChem Substance ID:
EC Number:
250-545-5
MDL number:
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grade

reagent grade

product line

Vetec

solubility

H2O: 50 mg/mL

antibiotic activity spectrum

viruses

storage temp.

2-8°C

SMILES string

CN[C@H]1C[C@@H](N)[C@H](O)[C@@H](O[C@@H]2O[C@H](CO)[C@H](O)[C@@H]3O[C@]4(O[C@H]([C@H](N)CO)[C@H](O)[C@H](O)[C@H]4O)O[C@H]23)[C@@H]1O

InChI

1S/C20H37N3O13/c1-23-7-2-5(21)9(26)15(10(7)27)33-19-17-16(11(28)8(4-25)32-19)35-20(36-17)18(31)13(30)12(29)14(34-20)6(22)3-24/h5-19,23-31H,2-4,21-22H2,1H3/t5-,6-,7+,8-,9+,10-,11+,12-,13+,14-,15-,16+,17+,18-,19+,20+/m1/s1

InChI key

GRRNUXAQVGOGFE-XKIAHZFYSA-N

Application


  • An engineered Streptomyces hygroscopicus aph 7 gene mediates dominant resistance against hygromycin B in Chlamydomonas reinhardtii:本文说明潮霉素B抗性基因在基因工程中的应用,促进藻类研究和生物燃料生产,体现潮霉素B在基因工程和筛选方案中的广泛用处(Berthold P et al., 2002)。

Biochem/physiol Actions

作用机制:本品通过诱导原核生物中m-RNA模板的误读,抑制蛋白质合成,具有抑制翻译的作用。

抗菌谱:潮霉素B对细菌、真菌和高等真核细胞有抑制作用。

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品

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历史批次信息供参考:

分析证书(COA)

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商品

LC/LC-MS method identifies 8 aminoglycosides in pork using Discovery® DSC-18 SPE and Ascentis® Express C18 UHPLC, per Chinese standards.


Bernd Becker et al.
ACS chemical biology, 8(1), 105-115 (2012-11-01)
Aminoglycoside antibiotics were among the first antibiotics discovered and used clinically. Although they have never completely fallen out of favor, their importance has waned due to the emergence of other broad-spectrum antibiotics with fewer side effects. Today, with the dramatically
Faisal Asghar Khattak et al.
BMC microbiology, 12, 204-204 (2012-09-13)
The genus Mycobacterium (M.) comprises highly pathogenic bacteria such as M. tuberculosis as well as environmental opportunistic bacteria called non-tuberculous mycobacteria (NTM). While the incidence of tuberculosis is declining in the developed world, infection rates by NTM are increasing. NTM
Bharat P Gurale et al.
The Journal of organic chemistry, 77(13), 5801-5807 (2012-06-06)
Concise and efficient syntheses of the aminocyclitol cores of hygromycin A (HMA) and methoxyhygromycin (MHM) have been achieved starting from readily available myo-inositol. Reductive cleavage of myo-inositol orthoformate to the corresponding 1,3-acetal, stereospecific introduction of the amino group via the



全球贸易项目编号

货号GTIN
V900372-1G04061826759394
V900372-250MG04061833352465