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Merck
CN

D3943

DAPH

≥98% (HPLC), solid

Synonym(s):

4,5-Dianilinophthalimide, 5,6-Bis(phenylamino)-1H-isoindole-1,3(2H)-dione, CGP 52411

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About This Item

Empirical Formula (Hill Notation):
C20H15N3O2
CAS Number:
Molecular Weight:
329.35
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Quality level:
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Quality Level

assay

≥98% (HPLC)

form

solid

color

orange

solubility

DMSO: >20 mg/mL, H2O: insoluble

storage temp.

2-8°C

SMILES string

O=C1NC(=O)c2cc(Nc3ccccc3)c(Nc4ccccc4)cc12

InChI

1S/C20H15N3O2/c24-19-15-11-17(21-13-7-3-1-4-8-13)18(12-16(15)20(25)23-19)22-14-9-5-2-6-10-14/h1-12,21-22H,(H,23,24,25)

InChI key

AAALVYBICLMAMA-UHFFFAOYSA-N

Gene Information

human ... EGFR(1956)

Biochem/physiol Actions

DAPH is an inhibitor of Aβ fibril formation; Protein tyrosine kinase inhibitor, specific for EGFR.

Features and Benefits

This compound is featured on the EGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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