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Merck
CN

1250008

USP

雌二醇

United States Pharmacopeia (USP) Reference Standard

别名:

β-雌二醇, 17β-雌二醇, 1,3,5-雌三烯-3,17β-二醇, 3,17β-二羟基-1,3,5(10)-雌三烯, 二氢卵泡素

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关于此项目

经验公式(希尔记法):
C18H24O2
化学文摘社编号:
分子量:
272.38
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1914275
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grade

pharmaceutical primary standard

API family

estradiol

manufacturer/tradename

USP

mp

176-180 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O[C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(O)=CC=C4[C@@]3([H])CC[C@@]21C

InChI

1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1

InChI key

VOXZDWNPVJITMN-ZBRFXRBCSA-N

Gene Information

human ... ESR1(2099)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Biochem/physiol Actions

绝经前卵巢分泌的主要雌激素。
绝经前卵巢分泌的主要雌激素。雌激素通过调节基因转录并因此调节蛋白质合成来指导胚胎发生和青春期女性表型的发展。 它还诱导促性腺激素的产生,进而诱导排卵。 暴露于雌二醇会增加乳腺癌的发生率和增殖。

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.


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pictograms

Health hazardEnvironment

signalword

Danger

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A

flash_point_f

Not applicable

flash_point_c

Not applicable

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

法规信息

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分析证书(COA)

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Estradiol and Norethindrone Acetate Tablets
United States Pharmacopeia, 44(6) (2023)
L-P Boulet
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 45(1), 75-86 (2014-10-18)
The prevalence of obesity has increased worldwide, and weight gain has been shown to influence the development and clinical expression of various conditions including asthma. The relationships between atopy and obesity remain uncertain, both in adults and in children. Although
Marie Mi Bonde et al.
Nucleic acids research, 42(20), 12847-12860 (2014-10-30)
Splicing reactions generally combine high speed with accuracy. However, some of the pre-mRNAs escape the nucleus with a retained intron. Intron retention can control gene expression and increase proteome diversity. We calculated the escape rate for the yeast PTC7 intron



全球贸易项目编号

货号GTIN
1250008-500MG04061838723284