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Grignard reagents

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Grignard Reagents
Our unparalleled portfolio of Grignard Reagents are used in reactions such as Grignard reaction to form a new carbon-carbon bond.
Grignard Reagents
Our unparalleled portfolio of Grignard Reagents are used in reactions such as Grignard reaction to form a new carbon-carbon bond.
Grignard Reagents
Our unparalleled portfolio of Grignard Reagents are used in reactions such as Grignard reaction to form a new carbon-carbon bond.
Mild Mg – Halogen Exchange
Substantial progress has been made in magnesium–halogen exchange reactions used for the preparation of functionalized Grignard reagents containing sensitive moieties such as ester or cyano groups.
Selective Metalation, Deprotonation, and Additions
Transformative reagents for selective metalation, deprotonation and nucleophilic additions have allowed for unprecedented selective converstions to reactive intermediates within a molecule which contains sensative functionalities under mild reactions.
Selective 1,2-Additions with LaCl3·2LiCl
While the 1,2-addition of Grignard reagents to ketones is undoubtedly a powerful transformation, oftentimes selectivity issues arising from competitive alpha-deprotonation detract from the use of these reagents.
有机锂试剂
我们的有机锂试剂对于已知键的成功形成(例如亲核加成和取代)以及有机合成新技术的开发至关重要。
Chemical Synthesis
Chemical Synthesis
Chemical Synthesis
Chemical Synthesis
New Reagents for Selective Metalation, Deprotonation, and 1,2-Additions
Sigma-Aldrich.com presents an article concerning New Reagents for Selective Metalation, Deprotonation, and 1,2-Additions.
Selective Metalations
Selective Metalations using i-PrMgCl·LiCl and s-BuMgCl·LiCl
Boronic Acids & Derivatives
We are pleased to provide a wide range of boronic acids & derivatives, including boronate esters, trifluoroborate salts, and MIDA boronate esters. All of our boronic acid derivatives are offered as alkyl, alkenyl, aryl and heteroaryl derivatives.
有机锌试剂
我们可提供多种有机锌试剂用于已知键的形式和有机合成新技术的开发。
PEPPSI™ Catalysts
Professor Mike Organ at York University, along with co-workers Dr. Chris O’Brien and Dr. Eric Kantchev, have developed an palladium N-heterocyclic-carbene (NHC) catalyst system. They reacted PdCl2with a bulky NHC ligand, 2,6-diisopropylphenyllimidazolium chloride (IPr), and an α-donating 3-chloropyridine ligand for
PEPPSI™ Catalysts
PEPPSI™ Catalysts are novel state-of-the-art catalyst that successfully performs cross-coupling niche reactions.
Super Silyl Protecting Groups
The super silyl group is a powerful tool for the synthetic chemist, showing great efficacy in various carbon–carbon bond forming reactions.
Chemistry & Biochemicals
Explore our wide range of chemistry and biochemical products and custom chemistry services for all your life science, chemical synthesis, lab chemicals, cheminformatics, and materials science applications.
Chemistry & Biochemicals
Explore our wide range of chemistry and biochemical products and custom chemistry services for all your life science, chemical synthesis, lab chemicals, cheminformatics, and materials science applications.
Molecular Monolayers on Silicon Surfaces
This article briefly reviews the methods and mechanisms for the formation of molecular monolayers on silicon surfaces, the properties of these monolayers and current perspectives regarding their application in molecular electronic and sensing applications.
Fluoroalkylation: Expansion of Togni Reagents
The fluoroalkylation toolbox now includes Togni reagents, hypervalent iodine perfluoroalkylation reagents, fluoroalkyl bromides, silanes, carboxylates, and sulfonyl fluorides for late stage fluoroalkylation.
Bottles & Cans
We offer a variety of packaging options for your application. Whether you need your solvent packaging in glass bottle, PVC coated bottle, Sure/Seal™ bottle or aluminum can, we package and solvent dispensing options to meet your needs.
Ellman's Sulfinamides
Ellman's sulfinamide is available in both enantiomeric and racemic forms for your research. This versatile and useful auxiliary has found extensive use both in academics and industry.
C-H官能团化
C-H官能团化是指通过选择性且受控的方式将C-H可靠、可预测地转换为C-C、C-N、C-O或C-X键。
有机反应工具箱
有机反应工具箱可为独特的化学反应提供构效关系来优化设计和控制小分子合成。
New Conducting and Semiconducting Polymers for Plastic Electronics
In the emerging field of organic printable electronics, such as OLEDs and organic photovoltaics (OPVs), there is a significant need for improved organic conducting and semiconducting materials. This paper reports our recent progress in two fields: 1) the development of
Mild Mg – Halogen Exchange
Substantial progress has been made in magnesium–halogen exchange reactions used for the preparation of functionalized Grignard reagents containing sensitive moieties such as ester or cyano groups.
Selective Metalation, Deprotonation, and Additions
Transformative reagents for selective metalation, deprotonation and nucleophilic additions have allowed for unprecedented selective converstions to reactive intermediates within a molecule which contains sensative functionalities under mild reactions.
Organolithium Reagents
Our organolithium reagents are critical to the successful formation of known bond formations (e.g. nucleophilic addition and substitution) and the development of new technologies in organic synthesis.
Selective 1,2-Additions with LaCl3·2LiCl
While the 1,2-addition of Grignard reagents to ketones is undoubtedly a powerful transformation, oftentimes selectivity issues arising from competitive alpha-deprotonation detract from the use of these reagents.
Organolithium Reagents
Our organolithium reagents are critical to the successful formation of known bond formations (e.g. nucleophilic addition and substitution) and the development of new technologies in organic synthesis.
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