Merck
CN
All Photos(2)

Documents

850375P

Avanti

18:1 (Δ9-Cis) PC (DOPC)

Avanti Polar Lipids

Sign Into View Organizational & Contract Pricing

Synonym(s):
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine; DOPC; PC(18:1(9Z)/18:1(9Z))
Empirical Formula (Hill Notation):
C44H84NO8P
CAS Number:
Molecular Weight:
786.11
NACRES:
NA.25

description

1,2-dioleoyl-sn-glycero-3-phosphocholine

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 1 g (850375P-1g)
pkg of 2 × 100 mg (850375P-200mg)
pkg of 5 × 100 mg (850375P-500mg)
pkg of 1 × 25 mg (850375P-25mg)

manufacturer/tradename

Avanti Polar Lipids

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O

InChI

1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,42H,6-19,24-41H2,1-5H3/b22-20-,23-21-/t42-/m0/s1

InChI key

SNKAWJBJQDLSFF-AOMFJDGTSA-N

Related Categories

General description

18:1 (Δ9-Cis) PC or 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) is an unsaturated phospholipid.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

18:1 (Δ9-Cis) PC (DOPC) has been used for reproducing the supramolecular structure of the synovial fluid. It may also be used in the liposome preparation and in the preparation of planar supported membranes.

Biochem/physiol Actions

18:1 (Δ9-Cis) PC or 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) is mainly used in liposome preparation to deliver drug in to the body. DOPC is used along with 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine (DPPC) for lipid bilayer generation.

Packaging

5 mL Clear Glass Sealed Ampule (850375P-200mg)
5 mL Clear Glass Sealed Ampule (850375P-25mg)
5 mL Clear Glass Sealed Ampule (850375P-500mg)
60 mL Amber Wide Mouth Screw Cap Glass Bottle (850375P-1g)

also commonly purchased with this product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

?Force-from-lipids? gating of mechanosensitive channels modulated by PUFAs
Ridone P, et al.
Journal of the Mechanical Behavior of Biomedical Materials, 79(5), 158-167 (2018)
General model of phospholipid bilayers in fluid phase within the single chain mean field theory
Guo Y, et al.
J. Chem. Phys. , 140(17), 05B604-05B601 (2014)
The size of lipid rafts: an atomic force microscopy study of ganglioside GM1 domains in sphingomyelin/DOPC/cholesterol membranes
Yuan C, et al.
Biophysical Journal, 82(5), 2526-2535 (2002)
Formation of nanopores in DiynePC-DPPC complex lipid bilayers triggered by on-demand photo-polymerization
Chun MJ, et al.
Royal Society of Chemistry Advances, 8(49), 27988-27994 (2018)
Role of the biomolecular interactions in the structure and tribological properties of synovial fluid
Mirea D, et al.
Tribology International, 59(5), 302-311 (2013)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service